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5-fluoro PB-22 (is an analytical reference material that is structurally categorized as a synthetic cannabinoid (CB).
It is a full agonist of human CB1 and CB2 receptors (pEC50s = 8.55 and 7.97, respectively).1,2 5-fluoro PB-22 potently and dose-dependently induces hypothermia and reduces heart rate in rats, mimicking the in vivo effects of Δ9-THC
Formal Name 1-(5-fluoropentyl)-8-quinolinyl ester-1H-indole-3-carboxylic acid
CAS Number 1400742-41-7
Molecular Formula C23H21FN2O2
Formula Weight 376.4
Formulation A neat solid
InChI Code InChI=1S/C23H21FN2O2/c24-13-4-1-5-15-26-16-19(18-10-2-3-11-20(18)26)23(27)28-21-12-6-8-17-9-7-14-25-22(17)21/h2-3,6-12,14,16H,1,4-5,13,15H2
InChI Key MBOCMBFDYVSGLJ-UHFFFAOYSA-N
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